WebAccordingly, FIP200, also known as the RB1-inducible coiled-coil protein 1 (RB1CC1), is a non-catalytic scaffolding protein. It regulates a wide range of cellular events, such as growth, proliferation, apoptosis and autophagy, through interactions with signaling proteins (e.g., PYK2, FAK, ActA, p53, TSC1, ASK1, TRAF2 and Stathmin) . WebPolyclonal antibodies were generated to regions of the RAI-1. The program Protean (DNASTAR) was used to select optimal peptide epitopes 15–20 residues in size. Freeware NetPhos was employed to check for probability of phosphorylation and freeware COILS was employed to avoid coiled-coil regions. Three different antibodies were generated as ...
(PDF) RB1CC1 Activates RB1 Pathway and Inhibits
WebHang Lu, 1, * Zhenjun Zhang, 2, * ... WERI-Rb1 and SO-RB-50 cell lines and normal human epithelial retinal cell ARPE-19 were ... pcDNA was used to construct rho-associated coiled-coil-containing protein kinase 1 (ROCK1) over-expression vector (pcDNA-ROCK1) and interference sequence (si-ROCK1). In addition, the above primer sequences for ... WebAutophagy is an evolutionarily conserved cellular process in which intracellular components are eliminated via lysosomal degradation to supply nutrients for organelle biogenesis and … cool toys for one year old
Truncating mutations of RB1CC1 in human breast cancer - Nature
Web北鱼生物,国内稳定同位素产品供货商,包括2H(氘代)、13C、15N、17O和18O等同位素产品,产品种类齐全,包括:无机物、有机物、糖类、氨基酸、维生素、胆汁酸、儿茶酚胺、类固醇、药物中间体、新生儿筛选所有标品及其系列同位素产品。稳定同位素标记物由于其质谱与对应的非标记元素的差 WebFigure 1 Percentage of the 11q13.3 amplicon expression in common ... de Lange T. Chromothripsis and Kataegis induced by telomere crisis. Cell. 2015;163(7):1641–1654. doi:10.1016/j ... Yang S, Wang W, et al. The interaction of Lin28A/Rho associated coiled-coil containing protein kinase2 accelerates the malignancy of ovarian cancer ... WebMar 1, 2012 · RB1-inducible coiled-coil 1 (RB1CC1; also known as FIP200) plays important roles in several biological pathways such as cell proliferation and autophagy. Evaluation … family tree gov