Nephrin antibody
WebAnti-Nephrin (Nphs1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Nephrin is encoded by the Nphs1 gene in human. Nephrin is a structural protein making the slit diaphragm in the glomerular podocytes. WebFeb 9, 2024 · A specific band was detected for Nephrin at approximately 185 kDa (as indicated) using 20 µg/mL of Sheep Anti-Human Nephrin Antigen Affinity-purified …
Nephrin antibody
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WebNephrin is a member of the immunoglobulin family of cell adhesion molecules that localizes to opposing sites of the secondary foot processes formed by podocytes, a specialized … WebSep 30, 2024 · We report our experience with a C57BL/6 FSGS model induced by polyclonal rabbit anti-mouse nephrin antibody (α-mNep Ab). Methods: α-mNep Ab, which was generated by genetic immunization, was ...
WebMay 4, 2012 · Get better batch-to-batch reproducibility with a recombinant antibody. Anti-Nephrin antibody [EPR20993] (ab216341) Research with confidence – consistent and reproducible results with every batch. Long … Web"Nephrin antibodies" comparison. At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs.
WebNov 3, 2024 · 17, 18 Anti-nephrin antibodies were detected in 29% of MCD patients in initial disease onset and then became undetectable in remission. 17 In these patients, delicate punctate IgG deposits were ... WebCells stained with primary antibody (green), and isotype control (orange). 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. Seems to play a role in the development or function of the kidney glomerular filtration barrier.
WebSep 1, 2024 · The effect of topiroxostat in anti-nephrin antibody (ANA)-induced podocyte injury. (a) Representative IF findings (upper panel), and the semi-quantitative data of immunostaining (lower panel) of podocyte functional molecules. Nephrin, podocin and podoplanin were observed as a continuous linear pattern along capillary loop in normal …
WebAug 18, 2024 · After red blood cell removal using ammonium chloride potassium lysis buffer and endothelial cell depletion using CD31 antibody (Biolegend, San Diego, CA, USA), nephrin-positive cells were prepared from minced murine kidneys using magnet-activated cell sorting with nephrin antibody (Thermo Fisher Scientific, Waltham, MA, USA). family\\u0027s c1WebBackground: Failure of the glomerular filtration barrier, primarily by loss of slit diaphragm architecture, underlies nephrotic syndrome in minimal change disease. The etiology … family\u0027s c4WebCatalog Number ab58968. Antibody Type Primary. Clonality Polyclonal. Applications Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot. Isotype IgG. Quantity 50 UG. Host Rabbit. Conjugate/Tag … co-op academy beckfieldWebAug 3, 2024 · nephrin Antibody (G-8) is a mouse monoclonal IgG 2a κ nephrin antibody, cited in 24 publications, provided at 200 µg/ml. raised against amino acids 23-322 mapping within an extracellular domain of nephrin of rat and human origin. nephrin Antibody (G-8) is recommended for detection of nephrin of mouse, rat and human origin by WB, IP, IF … family\\u0027s c6WebAll lanes : Anti-Nephrin antibody [EPR20993] (ab216341) at 1/1000 dilution Lane 1 : Mouse kidney lysate Lane 2 : Mouse spleen lysate Lysates/proteins at 10 µg per lane. … family\\u0027s c4WebMay 17, 2012 · Urinary nephrin levels (nephrinuria) were then measured in 66 patients with Type 2 diabetes and 10 healthy controls by an enzyme-linked immunosorbent assay (Exocell, Philadelphia, PA). When divided into groups according to normo-, micro-, and macroalbuminuria, nephrinuria was found to be present in 100% of diabetic patients with … family\\u0027s c5WebNephrin Antibody: Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. co op academy blackley