Methylthieno
WebHowever, the methosulphate reacted with aqueous potassium cyanide to give 6,9-dihydro-N-methylthieno[3,2-f]quinoline-9-carbonitrile which when oxidised with iodine in pyridine yielded 9-cyano-N-methylthieno[3,2-f]quinolinium iodide. Demethylation gave thieno [3,2-f]quinoline-9-carbonitrile. WebProducts on methylthieno are available at Ambeed. Browse Ambeed's methylthieno to find more products in Thiophenes. Free Sample; Deals; New Products; Bulk Products; About …
Methylthieno
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WebA mixture of 7-methylthieno[3,2-d]pyrirnidine-2,4(lH,3H)-dione (403 mg, 2.21 mmol) and phosphonyl chloride (8.0 mL, 86 mmol) was heated at 116 0 C for 4 h. Upon completion … WebThey are 7-methylthieno[3, 2-f ]quinoline and 9-methylthieno[3,... New heterocyclic bases with a condensed heterocyclic ring in the molecule are synthesized. They are 7 …
WebSupporting information for Identification of 3-aminothieno[2,3-b]pyridine-2-carboxamides and 4-aminobenzothieno[3,2-d]pyrimidines as LIMK1 Inhibitors Brad E. Sleebs,a Alla Levit,a Ian P. Street,a Hendrik Falk,a Tim Hammonds,b Ai Ching Wong,b Mark D. Charlesb and Jonathan B. Baella* aThe Walter and Eliza Hall Institute of Medical Research, 1G Royal … WebSelective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic. Chemical Name. 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno [2,3-b]pyridine-2-carboxamide. Biological Activity. Selective positive allosteric modulator of M4 receptor (KB = 200 nM, α = 35); increases the potency of acetylcholine by 40-fold.
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WebYu M et al., 2015, Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure-activity relationship analysis and biological evaluation., Eur J Med Chem CHEMBL1240885 MKNK1 Interaction Score: 61.83 Interaction Types & Directionality: n/a: Interaction Info:
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